The Pharmaceutical Research and Manufacturers of America (PhRMA), in a lengthy study aimed at discovering and developing ways for patients to live longer, healthier and more productive lives, concluded that successful treatment of disease with prescription medicines requires consistent use of the medicines as prescribed.
The cost of medication non-adherence is significant in terms of loss of life and monetary costs. According to the CDC, 20 to 30 percent of prescriptions are never filled, and in about 50 percent of cases, medication is not continued as prescribed.
When opioids are to be used to treat psychiatric or pain disorders, the practitioners must educate themselves regarding the neuroscience of opioids so that they can competently prescribe these medications for use in psychiatric and chronic pain syndromes. At a minimum, the treating healthcare professional should be aware of some of the more common medical side effects of the opioids.